ABSTRACT
The study explores the dynamics of a COVID-19 epidemic in multiple susceptible populations, including the various stages of vaccination administration. In the model, there are eight human compartments: completely susceptible;susceptible with dose-1 vaccination;susceptible with dose-2 vaccination;susceptible with booster dose vaccination;exposed;infected with and without symptoms, and recovered compartments. The biological feasibility of the model is analysed. The threshold value, R0, is derived using the next-generation matrix. The stability analysis of the equilibrium points was performed locally and globally using the threshold parameter of the model. The conditions determining disease persistence is obtained. The model is subjected to sensitivity analysis, and the most sensitive parameters are identified. Also, MATLAB is used to verify the mathematical outcomes of the system's dynamic behaviour and suggests that necessary steps should be taken to keep the spread of the omicron variant infectious disease under control. The findings of this study could aid health officials in their efforts to combat the spread of COVID-19. © 2022 International Association for Mathematics and Computers in Simulation (IMACS)
ABSTRACT
The forecasting of the nature and dynamics of emerging coronavirus (COVID-19) pandemic has gained a great concern for health care organizations and governments. The efforts aim to to suppress the rapid and global spread of its tentacles and also control the infection with the limited available resources. The aim of this work is to employ real data set to propose and analyze a compartmental discrete time COVID-19 pandemic model with non-linear incidence and hence predict and control its outbreak through dynamical research. The Basic Reproduction Number ( R 0 ) is calculated analytically to study the disease-free steady state ( R 0 < 1 ), and also the permanency case ( R 0 > 1 ) of the disease. Numerical results show that the transmission rates α > 0 and ß > 0 are quite effective in reducing the COVID-19 infections in India or any country. The fitting and predictive capability of the proposed discrete-time system are presented for relishing the effect of disease through stability analysis using real data sets.
ABSTRACT
The study explores the dynamics of a COVID-19 epidemic in multiple susceptible populations, including the various stages of vaccination administration. In the model, there are eight human compartments: completely susceptible;susceptible with dose-1 vaccination;susceptible with dose-2 vaccination;susceptible with booster dose vaccination;exposed;infected with and without symptoms, and recovered compartments. The biological feasibility of the model is analysed. The threshold value, R0, is derived using the next-generation matrix. The stability analysis of the equilibrium points was performed locally and globally using the threshold parameter of the model. The conditions determining disease persistence is obtained. The model is subjected to sensitivity analysis, and the most sensitive parameters are identified. Also, MATLAB is used to verify the mathematical outcomes of the system’s dynamic behaviour and suggests that necessary steps should be taken to keep the spread of the omicron variant infectious disease under control. The findings of this study could aid health officials in their efforts to combat the spread of COVID-19.
ABSTRACT
This paper attempts to describe the outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19) via an epidemic model. This virus has dissimilar effects in different countries. The number of new active coronavirus cases is increasing gradually across the globe. India is now in the second stage of COVID-19 spreading, it will be an epidemic very quickly if proper protection is not undertaken based on the database of the transmission of the disease. This paper is using the current data of COVID-19 for the mathematical modeling and its dynamical analysis. We bring in a new representation to appraise and manage the outbreak of infectious disease COVID-19 through SEQIR pandemic model, which is based on the supposition that the infected but undetected by testing individuals are send to quarantine during the incubation period. During the incubation period if any individual be infected by COVID-19, then that confirmed infected individuals are isolated and the necessary treatments are arranged so that they cannot taint the other residents in the community. Dynamics of the SEQIR model is presented by basic reproduction number R 0 and the comprehensive stability analysis. Numerical results are depicted through apt graphical appearances using the data of five states and India.
ABSTRACT
This paper is devoted to answering some questions using a mathematical model by analyzing India's first and second phases of the COVID-19 pandemic. A new mathematical model is introduced with a nonmonotonic incidence rate to incorporate the psychological effect of COVID-19 in society. The paper also discusses the local stability and global stability of an endemic equilibrium and a disease-free equilibrium. The basic reproduction number is evaluated using the proposed COVID-19 model for disease spread in India based on the actual data sets. The study of nonperiodic solutions at a positive equilibrium point is also analyzed. The model is rigorously studied using MATLAB to alert the decision-making bodies to hinder the emergence of any other pandemic outbreaks or the arrival of subsequent pandemic waves. This paper shows the excellent prediction of the first wave and very commanding for the second wave. The exciting results of the paper are as follows: (i) psychological effect on the human population has an impact on propagation; (ii) lockdown is a suitable technique mathematically to control the COVID spread; (iii) different variants produce different waves; (iv) the peak value always crosses its past value.
Subject(s)
COVID-19 , COVID-19/epidemiology , COVID-19/prevention & control , Communicable Disease Control/methods , Humans , Pandemics/prevention & control , SARS-CoV-2 , VaccinationABSTRACT
In this paper, a mathematical model of the COVID-19 pandemic with lockdown that provides a more accurate representation of the infection rate has been analyzed. In this model, the total population is divided into six compartments: the susceptible class, lockdown class, exposed class, asymptomatic infected class, symptomatic infected class, and recovered class. The basic reproduction number (R0) is calculated using the next-generation matrix method and presented graphically based on different progression rates and effective contact rates of infective individuals. The COVID-19 epidemic model exhibits the disease-free equilibrium and endemic equilibrium. The local and global stability analysis has been done at the disease-free and endemic equilibrium based on R0. The stability analysis of the model shows that the disease-free equilibrium is both locally and globally stable when R0<1, and the endemic equilibrium is locally and globally stable when R0>1 under some conditions. A control strategy including vaccination and treatment has been studied on this pandemic model with an objective functional to minimize. Finally, numerical simulation of the COVID-19 outbreak in India is carried out using MATLAB, highlighting the usefulness of the COVID-19 pandemic model and its mathematical analysis.
ABSTRACT
This study presents an optimal control strategy through a mathematical model of the Covid-19 outbreak without lock-down. The pandemic model analyses the lock-down effect without control strategy based on the current scenario of second wave data to control the rapid spread of the virus. The pandemic model has been discussed with respect to the basic reproduction number and stability analysis of disease-free and endemic equilibrium. A new optimal control problem with treatment is framed to minimize the vulnerable situation of the second wave. This system is applied to study the effects of vaccines and treatment controls. Numerical solutions and the graphical pre-sentation of the results predict the fate of India's second wave situation on account of the control strategy. Lastly, a comparative study with control and without control has been analysed for the exposed phase, infective phase, and recovery phase to understand the effectiveness of the controls. This model is used to estimate the total number of infected and active cases, deaths, and recoveries in order to control the disease using this system and studying the effects of vaccines and treatment controls. (c) 2022 THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).
ABSTRACT
In this study, we developed and analyzed a mathematical model for explaining the transmission dynamics of COVID‐19 in India. The proposed SIuIkR model is a modified version of the existing SIR model. Our model divides the infected class I of SIR model into two classes: Iu (unknown infected class) and Ik (known infected class). In addition, we consider R a recovered and reserved class, where susceptible people can hide them due to fear of the COVID‐19 infection. Furthermore, a non‐monotonic incidence function is deemed to incorporate the psychological effect of the novel coronavirus diseases on India's community. The epidemiological threshold parameter, namely the basic reproduction number, has been formulated and presented graphically. With this threshold parameter, the local and global stability analysis of the disease‐free equilibrium and the endemic proportion equilibrium based on disease persistence have been analyzed. Lastly, numerical results of long‐run prediction using MATLAB show that the fate of this situation is very harmful if people are not following the guidelines issued by the authority.
ABSTRACT
This paper presents the current situation and how to minimize its effect in India through a mathematical model of infectious Coronavirus disease (COVID-19). This model consists of six compartments to population classes consisting of susceptible, exposed, home quarantined, government quarantined, infected individuals in treatment, and recovered class. The basic reproduction number is calculated, and the stabilities of the proposed model at the disease-free equilibrium and endemic equilibrium are observed. The next crucial treatment control of the Covid-19 epidemic model is presented in India’s situation. An objective function is considered by incorporating the optimal infected individuals and the cost of necessary treatment. Finally, optimal control is achieved that minimizes our anticipated objective function. Numerical observations are presented utilizing MATLAB software to demonstrate the consistency of present-day representation from a realistic standpoint. © 2021 Pal et al.
ABSTRACT
In this paper, we consider a mathematical model to explain, understanding, and to forecast the outbreaks of COVID-19 in India. The model has four components leading to a system of fractional order differential equations incorporating the refuge concept to study the lockdown effect in controlling COVID-19 spread in India. We investigate the model using the concept of Caputo fractional-order derivative. The goal of this model is to estimate the number of total infected, active cases, deaths, as well as recoveries from COVID-19 to control or minimize the above issues in India. The existence, uniqueness, non-negativity, and boundedness of the solutions are established. In addition, the local and global asymptotic stability of the equilibrium points of the fractional-order system and the basic reproduction number are studied for understanding and prediction of the transmission of COVID-19 in India. The next step is to carry out sensitivity analysis to find out which parameter is the most dominant to affect the disease's endemicity. The results reveal that the parameters η , µ and ρ are the most dominant sensitivity indices towards the basic reproductive number. A numerical illustration is presented via computer simulations using MATLAB to show a realistic point of view.